Strictly for Information Only, Not for Medical advice. Version of May 12 2021.
This one-pager summarizes the therapy adopted by Dr Shankara Chetty, from South Africa, to help prevent COVID-19 from progressing towards severe disease. The document focuses on the 8th day onwards of COVID-19, i.e. the inflammatory phase. It does not cover the initial viral phase, for which early treatment protocols already exist and can be prescribed before. The document is for information only, not for therapeutic advice. If you catch COVID-19, please seek immediate medical help.
The 8th Day Therapy aims at mitigating a possible hypersensitivity reaction, that can trigger an inappropriate immune response, including a possible subsequent cytokine storm. This transition from the initial viral phase typically occurs on Day 8 after the first symptoms. It’s essential for the treating physician to establish as precisely as possible the first day of symptoms, to alert the patient of the date when a possible sudden aggravation of symptoms may occur. Shortness of breath is typically associated with this aggravation.
The 8th Day Therapy encompasses 4 distinct interventions. They sometimes follow a previously prescribed early treatment protocol. Possible drug interactions need to be carefully assessed.
Goal: To stop the hypersensitivity reaction, to stop the release of mediators and to prevent an inappropriate immune response, including a possible subsequent cytokine storm.
Medication: Prednisone 80mg dly x 1 week.
Note: Increase dose rapidly to get symptomatic relief quickly. CRP and IL6 values must show quick decline. Dose will vary according to variants and severity of reaction. Can go as high as 100mg tds for first few days. Wean off cautiously when CRP and IL6 are normal or patient is well for a few days. Those with prolonged reactions are difficult to wean, so consider adding Azathioprine 50mg dly to decrease steroid requirements.
Goal: To clear the histamines that have been released. Medications:
H1: Promethazine 25mg tds x 5 days or,
Levocetirizine 5mg bd x 1 month to follow Promethazine H2: Cimetidine 400mg x 1 month or,
another H2 blocker
Other anti-histamine drugs can be suitable
Goal: To clear the leukotrienes that have been released. Medication: Montelukast 10mg bd x 5 days then dly x 1 month Intervention #4: Blood Thinners
Goal: to clear platelet activating factors Medications:
Aspirin 325 mg dly x 1 month.
Add Xarelto 15 mg bd if D.Dimer is raised; decrease to 15 mg dly x 1 month once D.Dimer is normal
By Dr Shankara Chetty, MD, with the editorial assistance of JP Kiekens / covexit.com
Strictly for Information Only, Not for Medical advice. Version of May 12 2021.
A simple oxygen saturation meter will tell you if your body is absorbing oxygen. A low percentage means you need are not. This type of device clip on your finger and easy to use.
In New Zealand you can buy from https://www.trademe.co.nz/a/marketplace/health-beauty/medical-supplies/blood-pressure-monitors/listing/3369624067?bof=xf6qSX7a
Also google or search on Ebay.com or Amazon.com
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